Researchers at the University of
London have developed a new method for delivering vaccines directly into the
bloodstream. Professor Simon Cutting of Royal Holloway, University of London,
stated that instead of delivering the vaccine with a needle, vaccines based on
Bacillus spores can be delivered as a nasal spray, an oral liquid or capsule,
or a small soluble film placed under the tongue. Professor Cutting noted that
that spores are exceptionally stable vaccines based on Bacillus and do not
require cold storage, thus eliminating another issue with current vaccines.
With oral vaccines, the fear of needles is no longer a deterrent to getting
immunized, and the vaccine is safer to administer, particularly for countries
where HIV is prevalent. Also, the vaccines will be more cost-effective to make
and easier to keep fresh.
The technique was developed when
researchers discovered they could use “good bacteria” to administer vaccines.
Researchers found that Bacillus spores were perfect for transporting antigens,
which cause the immune system to produce antibodies to protect against them.
Professor Cutting has carried out trials to determine the effectiveness of
Bacillus-based vaccines for diseases such as influenza, TB, and tetanus.
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empowering people to make healthy choices to prevent the spread of the HIV
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