Search This Blog

Friday, December 31, 2010

CDC Tries to Make HIV Testing Routine

Under a law that took effect in October, health care providers in Ohio no longer have to obtain a patient's separate, informed consent before administering an HIV test. Although such consent is no longer required, providers still must inform patients of their right to anonymous testing.

At Cleveland's MetroHealth Medical Center, infectious-disease specialist Dr. Ann Avery recently led an analysis of electronic medical records on HIV testing there from 2002-07. The number of tests given rose each year, and an average of 0.75 percent of patients were HIV-positive. In 2007, 9,155 tests were conducted, and 48 were positive. Most screening during the years studied was in conjunction with outpatient care for pregnant women, Avery said.

Avery and her team then reviewed hospital and clinic encounters in 2008-09 for patients ages 13 to 64 who had not been diagnosed with HIV. This analysis involved 34,000 hospital admissions and 336,000 outpatient visits and found that:
*71.4 percent of patients in 2008 and 70.7 percent in 2009 had never undergone HIV testing at MetroHealth.
*Of those newly diagnosed with HIV, eight out of 10 had not been tested previously at MetroHealth, despite presenting for outpatient care or being admitted.
*Men were half as likely as women to have been tested.

In response to the findings, which Avery presented in October at the national conference of the Infectious Disease Society, MetroHealth modified its computerized health maintenance reminder to inform the primary physician about a patient's HIV test history. "That way, we can be a little more smart about this routine testing," Avery said.

In addition, MetroHealth is coaching its staff in the communication skills necessary to explain to patients, especially teenagers, the benefits of being tested for HIV.

Since 2006, CDC has recommended that persons ages 13 to 64 should be offered HIV testing as a part of routine medical care.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Tuesday, December 28, 2010

South Africa Program Cuts HIV Drug Prices 50%

A new antiretroviral drug program has halved the price the South African government will pay for HIV drugs, PlusNews reports.

The program has an estimated savings of $685 million and will allow the South African government to treat twice as many HIV-positive patients. However, few of the fixed dosed combinations have been included in the deal because of registration delays from the Medicines Control Council.

Fixed dose combinations allow for better adherence and fewer pharmacy errors. Health Minister Aaron Motsoaledi said he hoped the savings would help the 900,000 people who were diagnosed with the virus as a result of new HIV testing efforts.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Virginia to Move 760 ADAP Clients to Waiting List

For the first time in two decades, a sharp increase in enrollment has forced Virginia's medication assistance program for low-income, uninsured HIV and AIDS patients to limit who it serves.

Like several states, Virginia is struggling to accommodate increased need, which has been driven by a lagging economy, more HIV testing and diagnosed cases, and patients living longer on available treatments.

An estimated 760 of the patients with more stable immune systems will transition from Virginia's AIDS Drug

Assistance Program to a waiting list in the next few months because they don't meet the scaled-back eligibility requirements. An additional 400 new clients a year who would have qualified also will be placed on the waiting list, according to estimates.

It is likely Virginia's eastern region, which includes South Hampton Roads, will feel the pinch, as it represents about a third of the program's patients and the state's new HIV diagnoses.

However, officials with the Virginia Department of Health predicted that all patients who are no longer eligible for the program will find help through either Medicaid or drug companies' assistance programs.

State health workers are helping them find alternative sources for their medication.

"The focus is to make sure that they get their treatment for their HIV," said Maureen Dempsey, the state's chief deputy for public health.

Workers with an HIV/AIDS support program in Norfolk are worried about the logistics of applying for drug company charity and that those resources would eventually run dry.

"I can imagine that at some point, the patient assistance programs are going to get maxed out," said Stacie Walls-Beegle, executive director of Access AIDS Care.

Though anti-HIV medications don't cure an HIV infection, they can control the reproduction of the virus and slow the progression of related disease. In patients who miss dosages, the virus can replicate more rapidly and may develop a resistance to drugs.

The federal Ryan White program pays for almost 90 percent of the $20 million budget for Virginia's AIDS Drug Assistance Program. The state contributes the remainder.

Funding has been constant in recent years, state health officials said. As recently as 2006, the program was losing clients, according to a recent George Mason University report.

However, between spring 2007 and spring 2010, the total number of patients served per year grew 21 percent to 3,952, according to state health department statistics.

Between spring 2008 and spring 2009, the program paid an average of $1,254 a month for 1,649 patients, according to the George Mason report. From April to October of this year, though, the average monthly cost per patient rose to $1,283, with the program serving an average of 2,019 patients per month, according to the health department.

Also adding to the expense: Over the past few years, individual patient treatments have required more different drugs, said Kathy Hafford, director of the state health department's division of disease prevention.

Federal funding didn't keep pace because it's based on less recent data, Dempsey said. Money for the 12 months beginning in April 2010 was determined using the number of people living with HIV/AIDS in 2008.

Programs across the nation saw enrollment spikes in 2009.

As of Dec. 9, Virginia and eight other states had waiting lists totaling more than 4,500 patients, and 17 other states had taken steps similar to Virginia's to limit program costs, according to the National Alliance of State and Territorial AIDS Directors. At that time, Virginia reported 24 patients on its new waiting list.

To help contain costs, pharmaceutical companies earlier this year agreed to reduce medicine charges for AIDS Drug Assistance Programs. The federal government also awarded some extra money; Virginia received $400,000 of it.

"It was very helpful," Hafford said. "But it wasn't enough."

To stay within budget, state officials last month closed enrollment for new patients to everyone except pregnant women, children ages 18 or younger, and other patients receiving treatment for an active opportunistic infection.

They also decided to limit the drugs in the program to antiretrovirals, medications to prevent and treat opportunistic infections, and vaccines not available from another source.

The income criteria remains at 400 percent or below federal poverty levels, which amounts to $43,320 for one person.

Though both federal and state lawmakers have taken steps to provide the program more money in future budgets, Dempsey said Virginia's new rules likely would be in place until at least April 2012.

"If the ADAP funding stays flat and the demand stays as high as it is, we're going to have to continue our enrollment restrictions and assist people into other programs," she said.

Walls-Beegle said it's unfortunate that the drug program's cutbacks come at a time when many groups are diagnosing more HIV/AIDS patients and trying to get them into treatment.

"It's still a good thing that they're being identified, and they're knowing their status," she said. "It's another thing that we have to say, 'Oh, we want to help you, but then there's not that help that has been traditionally available by the government.' "


The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!


Source:
The Virginian-Pilot
December 19, 2010

HIV Orphan’s Fate Awaits Decision

The HIV-positive orphan girl, who was abandoned by her family members in Nalbari, will stay at a city-based community care centre for a few more weeks before the Assam State AIDS Control Society takes a decision on accepting the offer from organisations eager to take permanent care of the four-year-old.

The community care centre at Beharbari is run by Bharukha Public Welfare Trust, an NGO. The Assam State AIDS Control Society will seek permission from the National AIDS Control Organisation (NACO) to extend her stay at the community care centre at the Beharbari area in Guwahati where she is being taken care of.

Hem Chandra Barman, the joint director (care, support and treatment) of the society, said, “Though three organisations have contacted us offering to take care of the girl, we are not in favour of taking a hasty decision to send her outside the state. Her condition is improving and today she was seen playing with dolls, greeting people and taking food. We want to keep her here for a few more weeks before we decide. We will extend her stay and if necessary we will seek permission from NACO.”

According to NACO guidelines, an HIV-positive child can stay at a community care centre for only 15 days. The girl from Nalbari has already spent 12 days. “This is a special case. Till a permanent centre is decided on, we can allow extension of her stay at the community care centre,” NACO’s team leader (in-charge) in Guwahati Huidrom Rosemara said.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

HIV Orphan’s Fate Awaits Decision

The HIV-positive orphan girl, who was abandoned by her family members in Nalbari, will stay at a city-based community care centre for a few more weeks before the Assam State AIDS Control Society takes a decision on accepting the offer from organisations eager to take permanent care of the four-year-old.

The community care centre at Beharbari is run by Bharukha Public Welfare Trust, an NGO. The Assam State AIDS Control Society will seek permission from the National AIDS Control Organisation (NACO) to extend her stay at the community care centre at the Beharbari area in Guwahati where she is being taken care of.

Hem Chandra Barman, the joint director (care, support and treatment) of the society, said, “Though three organisations have contacted us offering to take care of the girl, we are not in favour of taking a hasty decision to send her outside the state. Her condition is improving and today she was seen playing with dolls, greeting people and taking food. We want to keep her here for a few more weeks before we decide. We will extend her stay and if necessary we will seek permission from NACO.”

According to NACO guidelines, an HIV-positive child can stay at a community care centre for only 15 days. The girl from Nalbari has already spent 12 days. “This is a special case. Till a permanent centre is decided on, we can allow extension of her stay at the community care centre,” NACO’s team leader (in-charge) in Guwahati Huidrom Rosemara said.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

HIV Orphan’s Fate Awaits Decision

The HIV-positive orphan girl, who was abandoned by her family members in Nalbari, will stay at a city-based community care centre for a few more weeks before the Assam State AIDS Control Society takes a decision on accepting the offer from organisations eager to take permanent care of the four-year-old.

The community care centre at Beharbari is run by Bharukha Public Welfare Trust, an NGO. The Assam State AIDS Control Society will seek permission from the National AIDS Control Organisation (NACO) to extend her stay at the community care centre at the Beharbari area in Guwahati where she is being taken care of.

Hem Chandra Barman, the joint director (care, support and treatment) of the society, said, “Though three organisations have contacted us offering to take care of the girl, we are not in favour of taking a hasty decision to send her outside the state. Her condition is improving and today she was seen playing with dolls, greeting people and taking food. We want to keep her here for a few more weeks before we decide. We will extend her stay and if necessary we will seek permission from NACO.”

According to NACO guidelines, an HIV-positive child can stay at a community care centre for only 15 days. The girl from Nalbari has already spent 12 days. “This is a special case. Till a permanent centre is decided on, we can allow extension of her stay at the community care centre,” NACO’s team leader (in-charge) in Guwahati Huidrom Rosemara said.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Iran Broadens its Battle against AIDS

When Iran discovered its first HIV case in a haemophiliac child in 1987, neither health professionals nor ordinary people could foresee a day when the threat of Aids would loom over the country.

Officially, the United Nations Development Programme in Iran puts the prevalence of HIV at less than 0.1 per cent of the 73m-strong population.

But Marzieh Vahid-Dastjerdi, the country's health minister, has repeatedly warned of the eruption of an "Aids volcano" and her ministry fears that anywhere between 83,000 and 120,000 people are HIV positive.

The main cause of transmission is intravenous drug injection but sexual transmission is rising at an alarming rate, experts say.

Ms Dastjerdi has recently urged young people to "behave morally" or, she warned, the HIV population might increase by five times in the near future.

Experts say rapid urbanisation and economic problems such as high inflation and unemployment have raised the marriage age and boosted divorce rates. These factors have led to increasing rates of drug addiction and sex outside marriage.

"Joblessness and having insufficient income to get married cause some young people to get caught in illegitimate sexual relations," says Massoud Mardani, a member of the National Committee to Care and Treat Aids, a state body.

Meanwhile, there is a concern about a significant rise in the number of women who are HIV positive. The health ministry says half of female sex workers may be HIV positive.

Abbas Sedaghat, head of the health ministry's Aids Office, says the increase in sexual transmission and the number of infected women has set off "alarm bells". He expresses hope that preventive measures, including educating young people of the consequences of their behaviour, could slow down the spread of Aids.

But experts warn that amphetamine stimulants and ecstasy-type substances that are increasingly used by young people are stoking high-risk behaviour.

The government has provided high-risk groups, including drug addicts and prisoners, with a range of HIV-related services. These include drug replacement therapies, antiretroviral treatment, voluntary testing and counselling, access to condoms and sterile needles and razors.

Aids tests, medicines and psychotherapy are free of charge in government-owned clinics.

In October, Michel Sidibe, UNAids executive director, praised Iran's work in addressing its HIV epidemic in prisons and among drug addicts as "progressive".

Iran's 250 prisons, rehabilitation camps and juvenile correctional centres house about 180,000 inmates. Nearly half of all inmates are imprisoned on drug-related charges.

However, some experts believe that Iran could do better.

Minoo Mohraz, head of Iranian Research Centre for HIV/Aids, affiliated to Tehran University of Medical Sciences (MCLS.PK - news) , says: "Our reaction against the virus has been a bit slow. The only way to control it is education through media."

According to the health ministry, only 16.5 per cent of young people aged between 15 and 24 are aware of the disease.

As a result, the authorities plan to implement a comprehensive five-year plan next year prioritising education of vulnerable women - including drug addicts, those married to drug users, and sex workers - and young people.

More than a decade after being diagnosed with HIV, Amir, a 35-year-old artist living in Tehran, is concerned about young people's widespread ignorance.

"When I was diagnosed, I could not even pronounce it and thought I would die in a week," he says.

He was infected with a contaminated needle used for tattooing an eagle on his shoulder, without being aware of the dangers.

Amir has not given up hope of leading a normal life. He has married a woman who is HIV positive and continues to play the tar and setar, Iran's traditional string music instruments.

"From that moment, I decided to go to schools, universities and to educate the youth not to be as ignorant as I was," he says.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

HIV Activist's '07 Murder Unsolved

HOUSTON — An HIV/AIDS advocate and activist was murdered three years ago Monday, and the case remains open and unsolved.

Steven DeCorte, 46, was attacked at his apartment in the 5500 block of Beverly Hill sometime before 6 a.m. Dec. 27, 2007.

He called 9-1-1 and told the dispatcher he was bleeding and needed an ambulance, officials said.

According to the Houston Police Department, DeCorte was already dead by the time emergency personnel arrived. He was found inside his apartment, lying by the front door.

Officials said he suffered a stab wound to the upper torso. There were no witnesses.

According to friends, DeCorte battled HIV for more than 20 years and served on numerous HIV advisory committees, including ACT Now, the Houston Area HIV Services Ryan White Planning Council and the Texas HIV Medication Advisory Committee with the Texas Department of State Health Services.

Crime Stoppers is offering a reward of up to $5,000 for any information that leads them to any suspect in this case. If you think of anything that may help police, call the (713) 222-8477 tips hotline or submit your tip online at www.crime-stoppers.org. All tipsters remain anonymous.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

AIDS Immunity is All in the Proteins!

It is the proteins which help some HIV infected people not end up having AIDS, a new study has suggested.

A large-scale genetic analysis has suggested that tiny changes in the structure of a protein help the immune system to recognize and destroy infected cells, reports Nature.

Most people who contract HIV eventually end up with full-blown AIDS as the virus replicates in their cells, reaching very high levels and damaging their immune systems.

However, the virus does not progress to this stage in about 1 out of every 300 infected people. These ''HIV controllers'' do not require treatment, because their bodies suppress the replication of the virus.

Bruce Walker of the Harvard University in Charlestown, first thought of carrying out the study when he recognized the clinical value of such HIV controllers.

"I realized that we could create a cohort by going directly to physicians around the world, and I thought we should figure out what is genetically unique about people who do well compared with people who do badly," he said.

Walker and his colleagues sampled the DNA of more than 900 HIV controllers. They compared it with the genetic code of 2,600 individuals with normal HIV infections, using a technique called a genome-wide association study (GWAS).

The GWAS tested single nucleotide polymorphism (SNP) variations - changes in one letter of DNA - at a million points in the genomes of these individuals, and found more than 300 sites that were statistically associated with control of HIV.

All the sites identified are in a region of the genome that codes for proteins involved in immune response, called HLA proteins. The researchers used regression analyses to narrow their search down to the four sites most strongly linked to HIV immunity.

It isn''t possible to tell from the statistics alone whether these sites cause HIV immunity themselves or are simply closely associated with others that do. But using a detailed map of the HLA regions of the genome, created as part of an earlier diabetes study2, the team pinpointed specific amino acids in the protein HLA-B that differed between controllers and people with normal infections.

These amino acids seemed to be behind the ability to control the virus.

"Out of the three billion nucleotides [that make up the human genome], we narrowed it down to a handful of amino acids that define the difference, each coded for by just three nucleotides," said Walker.

Changes in the amino acids identified by Walker''s team altered how HLA-B presents viral peptides from HIV to the immune system, but how this process differs between controllers and people with normal HIV infections remains unclear.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Findings in HIV/AIDS reported from Chinese Center for Disease Control and Prevention

A report, 'Scaling up the national methadone maintenance treatment program in China: achievements and challenges,' is newly published data in International Journal of Epidemiology. According to recent research published in the International Journal of Epidemiology, "China's methadone maintenance treatment program was initiated in 2004 as a small pilot project in just eight sites. It has since expanded into a nationwide program encompassing more than 680 clinics covering 27 provinces and serving some 242 000 heroin users by the end of 2009."

"The agencies that were tasked with the program's expansion have been confronted with many challenges, including high drop-out rates, poor cooperation between local governing authorities and poor service quality at the counter. In spite of these difficulties, ongoing evaluation has suggested reductions in heroin use, risky injection practices and, importantly, criminal behaviours among clients, which has thus provided the impetus for further expansion. Clinic services have been extended to offer clients a range of ancillary services, including HIV, syphilis and hepatitis C testing, information, education and communication, psychosocial support services and referrals for treatment of HIV, tuberculosis and sexually transmitted diseases. Cooperation between health and public security officials has improved through regular meetings and dialogue. However, institutional capacity building is still needed to deliver sustainable and standardized services that will ultimately improve! retention rates.

This article documents the steps China made in overcoming the many barriers to success of its methadone program," wrote W. Yin and colleagues, Chinese Center for Disease Control and Prevention.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Monday, December 27, 2010

Thursday, December 23, 2010

FDA Approves Gardasil Vaccine For Prevention Of Anal Cancer

The U.S. Food and Drug Administration announced today that it has approved Merck’s Gardasil vaccine for the prevention of human papillomavirus-related anal cancer in men and women ages 9 to 26 years.

“Treatment for anal cancer is challenging; the use of Gardasil as a method of prevention is important as it may result in fewer diagnoses and the subsequent surgery, radiation or chemotherapy that individuals need to endure,” said Dr. Karen Midthun, director of the Food and Drug Administration (FDA) Center for Biologics Evaluation and Research, in a press release.

The Gardasil vaccine (Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant) is the first vaccine to be approved for prevention of anal cancer. It works by targeting human papillomavirus (HPV) strains 6, 11, 16, and 18, which are most commonly associated with anal and other cancers.

The approval is based on clinical trial results showing that the vaccine is 78 percent effective in preventing precancerous anal lesions caused by HPV strains 16 and 18. These strains are responsible for an estimated 80 percent of anal cancers.

Anal cancer is increasingly a problem in people with HIV, as HPV is much more likely to cause anal cancer in HIV-positive men and women. Researchers have estimated that people with HIV are 30 to 50 times more likely to get anal cancer than people without HIV. In men who have sex with men this number is even higher, around 60 times more likely.

Antiretroviral therapy has not been shown to decrease the rates of anal cancer in men and women with HIV.

To effectively prevent anal cancer, Gardasil must be given before HPV is contracted, preferably when a person has had little or no prior sexual contact. The vaccine is given as three injections over six months.

Gardasil was already approved for prevention of cervical, vulvar, and vaginal cancers in women, and prevention of genital warts in both men and women.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

New HIV Treatment Found

German scientists have discovered a new way to treat HIV-AIDS by stopping the virus attaching itself to a human cell, which reduces side effects and the chance of viral resistance.


Researchers at Hannover Medical School and Ulm University have demonstrated that a peptide – similar to a protein but shorter – called VIR-576 stops the human immunodeficiency virus “docking” with a human cell.

“It is a completely new, effective therapy approach, from which we expect fewer side-effects,” said Professor Reinhold Schmidt from the Hannover Medical School.

Schmidt and his colleagues tested VIR-576 on 18 HIV-infected patients, in the first clinical study of the peptide. Their results were published the latest issue of the journal Science Translational Medicine.

The principle they have discovers also offers hope in the battles against viruses such as measles, hepatitis and Ebola.

A virus works by docking with a cell, hijacking its internal machinery and using it to make copies of itself. Usually, though not always, this makes the host sick, as is the case with HIV, which causes AIDS.

Medications already exist that block the attachment of HIV to human cells but these work either on or inside the cell.

“Because our peptide works directly on the virus rather than on the cell, certain side effects do not occur,” Schmidt said.

Furthermore, the emergence of viral resistance was less likely than with existing medications because the peptide binds to a part of the virus that never changes.

Highly effective drugs have existed since the mid-1990s that prevent the HIV virus from multiplying. As a result, people infected with HIV in wealthy countries such as Germany have an almost normal life-expectancy, although serious complications can arise, such as strokes and liver damage.

At present the new therapy must be given by transfusion, making it impractical as a treatment for wide use.

“Our goal is to develop a molecule that can be given as a tablet,” Schmidt said.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

San Francisco Study Finds Transmission Of Drug Resistant HIV Still Common, Despite New Medications

Results of a study published this month suggest that transmission of drug-resistant HIV remains prevalent in San Francisco, despite the introduction of new antiretroviral drugs such as Isentress and Selzentry.

The researchers concluded that transmitted drug resistance is still a problem and emphasized the need for early diagnosis and aggressive treatment strategies for people with drug-resistant HIV.

HIV that is resistant to treatment with antiretrovirals is one of the most common reasons that treatments fail. When people with drug-resistant HIV pass their virus on to others, those newly infected people have fewer treatment options.

Drug-resistant HIV is usually transmitted by people who are undergoing antiretroviral therapy but fail to achieve viral suppression (an undetectable amount of HIV in the bloodstream), or by people who acquire drug-resistant HIV and transmit it before beginning antiretroviral therapy.

As more and more HIV-positive people take antiretroviral drugs for longer lengths of time, the prevalence of drug-resistant HIV has increasingly become a cause for concern. In many areas, 10 percent to 20 percent of new HIV infections involve transmission of drug-resistant HIV.

Beginning in late 2007, new HIV medications including Isentress (raltegravir), Selzentry (maraviroc), and Intelence (etravirine) were introduced.

Researchers predicted that these newer antiretrovirals would better suppress transmission of drug-resistant forms of HIV if the main driver was transmission by people on antiretroviral therapy, since the new drugs would be better at suppressing HIV that is resistant to older medications.

Conversely, researchers hypothesized that if the main driver of transmitted drug resistance was treatment-naïve people with drug-resistant HIV, the impact of improved antiretroviral therapy would be minimal or delayed until the new drugs become widely available.

In this study, the researchers tried to determine whether the new antiretrovirals had an effect on transmission rates for drug-resistant HIV in the years since they were approved. To do so, they used results from a study that was designed to measure rates of transmitted drug resistance between 2002 and 2009.

The study included 372 people in San Francisco who had tested positive for HIV within 12 months of enrollment. Most of the participants (96 percent) were men who have sex with men; 9 percent of participants were injection drug users.

Participants were divided into two groups: those who tested positive for HIV between 2005 and 2007 and those who tested positive between 2008 and 2009. This allowed researchers to compare the prevalence of transmitted drug resistance before and after the introduction of new antiretrovirals in late 2007.

The researchers analyzed participants’ CD4 cell counts, viral load, and the presence of any drug resistance mutations displayed by their HIV.

Results showed that the prevalence of transmitted drug resistance more than tripled between 2003 and 2007 from 7 percent in 2003 to 24 percent in 2007. Between 2008 and 2009, the rate dropped to 15 percent of participants.

However, the researchers concluded that the difference was not statistically significant, and that overall, the chances of acquiring drug-resistant HIV in 2008 to 2009 were not significantly lower than the chances of acquiring drug-resistant HIV in 2005 to 2007.

The researchers listed two possible explanations for the study results: (1) poor antiretroviral therapy adherence and/or poor medical care in people who are on antiretroviral therapy or (2) considerable transmission of drug resistance via treatment-naïve individuals. Since other studies have indicated that more HIV-positive people in San Francisco have successfully achieved viral suppression in recent years, the researchers thought the second explanation was more likely.

The study authors stressed that there is a scarcity of data on the use of new antiretroviral medications in San Francisco and warned that delayed uptake of the new drugs will have a delayed impact on transmission of drug-resistant HIV.

As a result, they suggested that longer studies with participants from broader geographic areas are needed to allow for better comparisons of transmitted drug resistance rates before and after the introduction of novel anti-HIV drugs.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Effort Supports HIV/AIDS Patients While Promoting Safe Sex

The St. Louis Effort for AIDS (EFA) provides free, confidential HIV testing and treatment referral to residents in the seven-county metropolitan area.

Data from the Missouri Department of Health and Senior Services show the region reported 258 new HIV cases in 2009. Among male patients last year, black men comprised nearly 58 percent of new HIV cases and more than 59 percent of new AIDS cases. Among female cases in 2009, black women made up almost 84 percent of new HIV infections and roughly 87 percent of new AIDS diagnoses.

EFA Executive Director Cheryl Oliver said the goal is to get those who test HIV-positive into care and treatment. "Of the 2,384 people living with HIV/AIDS with no HIV care in the St. Louis region, over half - 51 percent - were African Americans," she said.

Oliver said testing is conducted in the group's RV or at its unmarked building. "We go to where the homeless congregate . out to where we know the 'strolls' are . where we know there is some drug use," she said of the mobile outreach.

"We schedule regular mobile testing unit days at a number of sites," Oliver continued. "We really try to set up some consistency, and then with our other high-risk areas we get out there as often as we can so people know that we are coming."

EFA employs 16 caseworkers to assist clients. "If someone tests positive there is rapid action protocol in place to get their info into the system so they can get case management services within 24 to 48 hours," Oliver said. "For drug use, we refer them into a drug rehab program. If they are homeless, we get them into housing - Doorways. If they have no food, we get them to Food Outreach."

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Utahns Don't Expect Swift Widespread Use of AIDS Pill that Helps Gay Men Avoid HIV Infection

Utah HIV/AIDS physicians and advocates are reacting cautiously to news that an already approved HIV treatment can help prevent healthy gay men from becoming infected.

The study involved men who have sex with men, and transgender persons who have sex with men. Among those who took daily emtricitabine plus tenofovir (Truvada), and who also were provided condoms, counseling, and other prevention services, the infection risk was cut by 43.8 percent. Participants who took the pills most faithfully had even more protection, up to 72.8 percent.

Dr. Kevin Fenton, head of CDC's National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, called the study's results "a major advance" in the fight against AIDS, but he cautioned the pills "should never be seen as a first line of defense against HIV."

Jennifer Brown, an epidemiologist with the Utah Department of Health who oversees the state's AIDS Drug Assistance Program (ADAP), agrees. And she cautioned that further research is needed, for example studying the possibility of drug resistance.

"It's another tool," said Dr. Claudia Goulston, who treats HIV patients at the University of Utah Hospital. "Taking a medication isn't that easy," she said, raising the issues of cost, side effects, and resistance.

Truvada costs from $5,000 to $14,000 a year in the United States. Brown said it is unclear whether federal rules would allow purchasing Truvada for uninfected persons through ADAP. Even if this were permitted, she cringes at spending the program's limited resources that way. "We're struggling to keep our patients who are HIV-positive on the program," she said.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

HIV/AIDS Patients Scrambling to Cover Cost of Medications

As part of its cost-containment strategy, Virginia's AIDS Drug Assistance Program has announced plans to push 760 current clients with relatively stable immune systems out of ADAP and onto a waiting list.

About 400 new ADAP applicants a year who would have qualified for the program under earlier, less-stringent requirements also will be placed on the list. As of Dec. 16, Virginia's ADAP waiting list held 59 names, according to the National Alliance of State & Territorial AIDS Directors.

State health officials believe all patients no longer ADAP-eligible can access treatment through Medicaid or assistance programs offered by pharmaceutical companies. State health workers are assisting patients to this end.

AIDS advocates, however, are not as optimistic about support from the private sector.

"I can imagine that, at some point, the patient assistance programs are going to get maxed out," said Stacie Walls-Beegle, executive director of Access AIDS Care in Norfolk. Advocates also worried about the logistics of the application process.

Federal government funds account for 90 percent of Virginia ADAP's $20 million annual budget, with the state providing the remainder. Funding has been flat in recent years, state health officials said. Between spring 2007 and spring 2010, the number of Virginia ADAP clients grew 21 percent. From April to October this year, it served an average 2,019 patients at cost of $1,283 per patient each month.

The state ADAP's new rules likely will remain in place until April 2012, said Maureen Dempsey, Virginia's chief deputy for public health. "If the ADAP funding stays flat and the demand stays as high as it is, we're going to have to continue our enrollment restrictions and assist people into other programs," she said.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

HIV Cases Rise in Philippines, Asia

Even as HIV prevalence stabilizes in many parts of the world, it continues to rise among men who have sex with men and among transgender persons in the Philippines and major Asian cities, according to the UN Development Program.

The situation may worsen further, UNDP said, unless nations strengthen their city-level responses. "We at the UN firmly believe that the key to achieving the MDGs [Millennium Development Goals] is through the localization of responses," said Renaud Meyer, UNDP's country director for the Philippines.

UNDP reported some success with its HIV prevention efforts, but it added that too few MSM and transgender persons are being reached by the programs. A recent UNDP study of Asia found that just 9 percent to 20 percent of MSM were covered by HIV services - falling far short of the MDG target of universal access to HIV prevention, treatment, and support. Clifton Cortez, UNDP's HIV practice leader for Asia-Pacific, said progress is being thwarted by challenges including restrictive legal environments and selective enforcement policies.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Sex Education Update with Net in Mind

Needham Public Schools (NPS) is updating its sex education curriculum to help students handle issues arising from new social networking and technology. A Health Advisory Council subcommittee, which developed the proposed program over the past two years, will present the curriculum to the School Committee at the end of January.

In the lead-up, NPS Wellness Program Director Kathy Pinkham has briefed parents about the lessons, and she hopes to have a website parents can peruse online before the winter break. "We really looked at this as a relationship with parents," she said. Ongoing information sessions also are planned after the break.

Under the proposal, homework assignments involving parental discussion around a series of questions would be expanded from fifth grade, where they have been successful, to other grades, Pinkham said. Materials from sex education classes would be taken home for students' parents, encouraging their involvement.

The curriculum aims to help students develop mature attitudes about sex in the Internet era, in which sexual encounters may begin with texting, Pinkham said.

"The culture has changed," Pinkham said. "It used to be people got married at 18, 19, 20 or 21. Now it's later and later. We will put it into context of what they want in life and their goals." In addition to anatomy, STD and abstinence components, the curriculum focuses on delaying sex and giving students the tools needed for healthy sex and relationships when they are adults, she said.

One theme will be the importance of face-to-face as opposed to electronic interactions, which can cloud decision-making. "Sometimes people end up with someone else because of happenstance," Pinkham said. "We will emphasize the importance of face-to-face communication, and that spending time together is important."

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Counselor Takes STD Testing to the Community with Comfortable Alternative

Young people come to Delbert Fullum's apartment in Wilkinsburg to hang out, play video games or cards, and to get tested for STDs and HIV.

Fullum is a certified HIV tester and counselor with One Church, a Christian church that since 2007 has contracted with the state and county health departments to serve as a designated testing site. Fullum offered his home as an adjunct site in 2008 after finding that many black youths were hesitant to get tested at church or during community events.

Friends, neighbors, family members, and friends of friends come to Fullum's home during the parties he hosts twice monthly to reach new people. Fullum also conducts testing at small house parties and other events throughout the region. The Allegheny County Health Department received 164 HIV samples from One Church between January and June of this year, and church founder Deryck Tines said most were Fullum's work.

"Although there are places to get tested in Wilkinsburg, no one is doing it like Del is doing it," said Tines. "He has come up with different incentives, like if you get tested, you get a free hour of studio time" in his apartment, Tines noted.

Fullum attributes his success to being seen as a peer. His easy demeanor is likely to get a youth's attention, but Fullum is careful in how he crafts his message. "It's all about how you phrase your words," he said. "I'll tell them, 'I'm not trying to get in your business. It's for your own benefit.'" He also emphasizes how HIV and other STDs disproportionately affect African Americans, particularly youths.

"[The home-based approach] alleviates a lot of the in-between stuff, the procrastinating," said Fullum.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Wednesday, December 22, 2010

New HIV/AIDS research has been reported by B.G. Williams et al

According to a study from Stellenbosch, South Africa, "HIV has increased the incidence of tuberculosis (TB) by up to sevenfold in African countries, but antiretroviral therapy (ART) reduces the incidence of AIDS-related TB. We use a mathematical model to investigate the short-term and long-term impacts of ART on the incidence of TB, assuming that people are tested for HIV once a year, on average, and start ART at a fixed time after HIV seroconversion or at a fixed CD4(+) cell count."

"We fit the model to trend data on HIV prevalence and TB incidence in nine countries in sub-Saharan Africa. If HIV-positive people start ART within 5 y of seroconversion, the incidence of AIDS-related TB in 2015 will be reduced by 48% (range: 37-55%). Long-term reductions depend sensitively on the delay to starting ART. If treatment is started 5, 2, or 1 y after HIV seroconversion, or as soon as people test positive, the incidence in 2050 will be reduced by 66% (range: 57-80%), 95% (range: 93-96%), 97.7% (range: 96.9-98.2%) and 98.4% (range: 97.8-98.9%), respectively. In the countries considered here, early ART could avert 0.71 +/- 0.36 [95% confidence interval (CI)] million of 3.4 million cases of TB between 2010 and 2015 and 5.8 +/- 2.9 (95% CI) million of 15 million cases between 2015 and 2050," wrote B.G. Williams and colleagues.

The researchers concluded: "As more countries provide ART at higher CD4(+) cell counts, the impact on TB should be investigated to test the predictions of this model."

Williams and colleagues published the results of their research in Proceedings of the National Academy of Sciences of the United States of America (Antiretroviral therapy for tuberculosis control in nine African countries. Proceedings of the National Academy of Sciences of the United States of America, 2010;107(45):19485-19489).

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Kaiser Permanente Program Provides Message in Edgy, Relevant Manner

A theatrical program sponsored by Kaiser Permanente debunked myths and candidly discussed the realities of engaging in early sex during a recent performance for National City teens.

At Sweetwater High School, some 700 students in grades nine through 12 watched an hour-long Kaiser Permanente Educational Theater play entitled "What Goes Around." Five professionally trained actors performed for the kids, alternating between satire, musical numbers, and monologues. The discussions ranged from safe sex and abstinence to the repercussions of unsafe sexual practices.

The program weaved in radio hits, statistics, and videos. The tale of "Eli" and "Alicia" concludes with each having contracted an STD and realizing the sexual pasts of their partners made them susceptible to infections. At the end, students received wallets with information on how to contact a clinic and access additional resources.

"We hope to empower them," said lead actress Nikki Mckenzie. "We are not here with an agenda, so we are not here to tell them how to live their lives. We are just here to give them some medical information so they can make educated choices."

"What I hope they walk away with is that they need to take control of themselves and be responsible for what they do, and if that means they are going to have sex, then they need to make good choices about that and there's plenty of places in the county to get protection," said Michelle Bell, district coordinator of health services.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Refocus on Prevention and Education to Make Progress on AIDS, Say US Scientists

Preventing new infections should be the priority of the long-term response to HIV/AIDS in Africa, according to a recent US Institute of Medicine (IOM) report.

In 2008, more than 33 million people had HIV/AIDS globally, including 22.4 million in Africa. "More than 90 percent of the 2.7 million new infections reported that year occurred in Africa," the institute noted in a statement. "By 2020, the number of infected people in Africa will grow to over 30 million, with just 7 million of the approximately 12 million who should be treated under current guidelines likely able to receive ART [antiretroviral therapy]," estimated the IOM committee that authored the report.

Though the US President's Emergency Plan for AIDS Relief (PEPFAR) requires the nations it assists to have a five-year HIV/AIDS strategy, the IOM report urges target countries to adopt a 10-year view.

The long-term costs of treatment are "not sustainable for the foreseeable future," the report states. "Already in Uganda and a few other nations, we don't have enough health care workers or ART to meet demands, and health centers are increasingly turning away patients who need these drugs to survive," said David Serwadda, professor and former dean of Makerere University's School of Public Health in Kampala, and IOM committee co-chair. "There is an urgent need for African countries and the US to share responsibility and initiate systematic planning now for the future. If we don't act to prevent new infections, we will witness an exponential increase in deaths and orphaned children in sub-Saharan Africa in just a couple of decades."

"I am deeply disappointed with this report," said Greg Gonsalves, a treatment activist who has worked in the United States and southern Africa. "It looks like it could have been written 10-15 years ago. It's a capitulation to the old guard in health and development . [that led to] crumbling health systems, dead mothers and babies, new epidemics and revivals of old ones."

Scaling up treatment "has not been rapid enough to solve the problems of this epidemic, and we have come full circle, back to the emphasis on prevention," said committee member Mead Over of the Center for Global Development in Washington. Incentives should be used to encourage HIV prevention, he added.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Threat of a Perfect Storm - AIDS and a Fresh Food Crisis

need external food assistance, 22 are in sub-Saharan Africa, according to the World Food Program. And the most vulnerable countries also have many people with HIV/AIDS.

"When food prices are putting nutritious food out of reach of people living with HIV and AIDS, it becomes an immediate crisis," said Scott Drimie, a research fellow with the International Food Policy Research Institute (IFPRI).

"A national census report [in Malawi] clearly shows that a high percentage of farmers spend a lot of time nursing sick relatives," said Sam Bota, country coordinator for IFPRI's Regional Network on AIDS, Livelihoods and Food Security (RENEWAL). "And after death, they lose a lot of time, sometimes as long as 20 days for the funeral, all that is a loss of productive time."

Across sub-Saharan Africa, climate changes have made the timing and frequency of rains uncertain, pushing yields down and causing farmers to switch to less familiar crops. In Malawi and Zambia, studies have found agriculture extension services are also taking a hit and affecting food security. Malawi has a 46 percent vacancy for jobs in this sector due to AIDS-related deaths. This loss carries well over into productivity, Bota said.

"Sudden increases in food insecurity can lead to distress migration as people search for food and work," Stuart Gillespie, director of RENEWAL, wrote in 2008. "Mobility is a marker of enhanced risk of HIV exposure, both for the person moving and for adults who may remain at home."

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Homophobia Sweeping Africa Like a Disease, Says Rights Group

The African Union must end its silence concerning homophobia on the continent and take urgent measures to stop this "growing and insidious contagion," the group AIDS-Free World says.

"The problem is definitely getting worse," said Paula Donovan, the organization's co-director. "Homophobia seems to be spreading like a contagion from country to country in Africa. And the efforts to criminalize homosexuality . [have] been taken up by increasing numbers of parliaments and promoted by increasing numbers of African leaders, including heads of state and prime ministers."

Uganda has recently considered laws that would impose harsh penalties for homosexual acts, with one measure calling for the death penalty in some cases. A gay couple in Malawi was prosecuted after their relationship became public. Other such incidents have occurred in Kenya, Zimbabwe, and recently, Ghana, said Donovan.

Many African leaders have called for the end of stigma and discrimination against people living with HIV/AIDS, Donovan acknowledged. However, "It's been pointed too narrowly at people who are already HIV-positive," she said. "Tolerance, openness, and refusal to discriminate have to apply to people before they are HIV-positive, as well as after." "As long as you discriminate against people and drive them into the margins of society, then you're going to exacerbate your HIV problems."

Donavan said she is "not quite sure what happened to trigger this new wave of homophobia across Africa," where national leaders historically have declared homosexuality a Western phenomenon that did not exist on the continent.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Thousands on HIV Drugs Desperate amid Budget Woes

The recession has driven more patients to seek help from AIDS Drug Assistance Programs, and many states have been unable to meet the demand for ADAP services. As a result, thousands of HIV patients are left with uncertain access to treatment.

In nine states, at least 4,732 people were on ADAP waiting lists as of Dec. 16, according to the National Alliance of State & Territorial AIDS Directors. At least 19 states have taken measures such as capping enrollment, dropping patients under newly lowered income limits, creating waiting lists, and dropping coverage of certain drugs or tests. In five states, more than 300 people lost ADAP coverage this year under recently lowered income limits. By February, hundreds more could be dropped under state plans, NASTAD says.

Health officials and advocates believe most - but not all - patients on the waiting lists are getting antiretroviral therapy free from pharmaceutical assistance programs. An unknown number do not qualify for help due to patchy coverage and eligibility rules that vary by drug company. These stipulations - not a physician's counsel - ultimately can determine what antiretroviral regimen a patient winds up taking.

The House of Representatives recently approved $60 million more for ADAPs in the fiscal year beginning April 1. But the Senate has not passed the measure, and it does nothing for this fiscal year, said Ann Lefert of NASTAD. A $25 million infusion over the summer helped some states eliminate waiting lists, but it fell about $100 million short of need. Now ADAP waiting lists are bigger than ever before, she said.

Despite the growing need, Legislatures in 12 states have cut the amount they allocate to their own ADAP to supplement the federal contribution.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Monday, December 20, 2010

Stigma Blocks HIV Prevention for MSM, Transgender People

A new study shows that human rights violations, discrimination and violence are a major barrier to HIV prevention and treatment for men who have sex with men (MSM) and transgender people, according to a statement by the Global Forum on MSM & HIV (MSMGF).

The study of in-depth interviews, conducted by MSMGF and commissioned by the World Health Organization, cites five major factors as severe obstacles to access: homophobia and transphobia, HIV stigma, criminalization and repressive policies, lack of awareness among providers, and safety.

Follow the link below to read the MSMGF report.

http://msmgf.org/files/msmgf//About_Us/Publications/WHO_Report1.pdf

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

CDC Releases Sexually Transmitted Diseases Treatment Guidelines, 2010 Edition

The Centers for Disease Control and Prevention has released the 2010 Sexually Transmitted Diseases Treatment Guidelines.

The guidelines can be found at the following link: http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5912a1.htm?s_cid=rr5912a...

Special Note: Please refer to page 50 for important information regarding the treatment of uncomplicated gonococcal infections of the cervix, urethra and rectum with Ceftriaxone 250 IM in a single dose or if not an option Cefixime 400 mg orally in a single dose PLUS Azithromycin 1g orally in a single dose or Doxycycline 100 mg a day for 7 days regardless if Chlamydia has been ruled out. In addition the treatment recommendation for uncomplicated gonococcal infections of the pharynex has been changed to Ceftriaxone 250 IM in a single dose PLUS Azitromycin 1g orally in a single dose or Doxycycline 100 mg a day for 7 days. This change can be found on page 51 of the guidelines.

The Friends of AIDS Foundation is currently reviewing the 2010 guidelines and will be providing updates in the near future on changes compared with the 2006 STD treatment guidelines.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Cambodia Calls for More Attention to Fight Against HIV/AIDS

On Tuesday, participants at Cambodia's third symposium on HIV/AIDS prevention, care and treatment said improved efforts and partnerships are needed to sustain the battle against HIV/AIDS.

About 300 Cambodian and international delegates attended the two-day conference, organized by the National Center for HIV/AIDS, Dermatology and STD.

An estimated 56,200 Cambodians are living with HIV/AIDS. As of the third quarter of 2010, the country was supplying antiretroviral treatment to 41,669 patients, including 4,003 children - covering more than 90 percent of those in need. "Our priorities ahead will be to prevent the second wave of HIV epidemic through more focus on targeted interventions among most at-risk populations, and to work towards the virtual elimination of pediatric HIV infection," Health Minister Mam Bunheng said at Tuesday's opening ceremony.


The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Assistant Pastor Urges Leaders, Congregations to Play a Bigger Role in Fight Against HIV

Love and acceptance of people living with HIV in the black community was the theme of a World AIDS Day event in Gainesville.

The banquet service at the Eastside Recreation Center was led by Dr. Ruby Davenport, assistant pastor of Faith Tabernacle of Praise Missionary Baptist Church and executive director of FAITH (Finding Alternatives That Initiate and Transform Hope) Inc. The event was sponsored by the Florida Department of Health and FAITH Inc.

The Rev. Dr. Andrew McRae, pastor of Faith Tabernacle, initiated the church's quest to help prevent the spread of HIV and to show love and compassion to those affected by the virus. "There ought to be something inside of you that makes you want to do something, too," Davenport told attendees.

Davenport called on area churches to become more involved in the fight against HIV/AIDS. She expressed concern over the stigma the disease has in the black community, particularly in churches. It is only because of God's grace and mercy that many more in the church community have not been affected or infected, she said.

In 2009, FAITH Inc. received a three-year state grant to educate churches about HIV/AIDS and how they can help. It took one-and-a-half years for most local pastors to come around, Davenport noted.

Bobby Davis, HIV/AIDS program director at the Alachua County Health Department, discussed the epidemic and noted that the poor and uninsured typically are the worst-affected.

A moment of silence was held for those who have died from HIV/AIDS, during which a girl placed balloons in the center of the room as people called out the names of loved ones they had lost.


The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

City''s Wrapper Design Contest Aims to Promote Use of Condoms

Health officials in Philadelphia are holding an open contest to choose a graphic that will be printed on the wrappers of condoms distributed during a citywide prevention campaign. Compared with other Pennsylvanians, city residents are about five times more likely to have chlamydia, six times more likely to have gonorrhea and 40 times more likely to have syphilis, according to the city health department.

The contest is modeled after one in New York City, which began offering its own themed condoms in 2007 and held its first condom-wrapper design contest last year. More than 600 entries were submitted, and 15,000 votes were cast.

"What we are always trying to do is be creative about keeping condoms on people's mind so when they need them they put them on their bodies," said Monica Sweeney, assistant commissioner for New York City's Bureau of HIV/AIDS Prevention and Control. New York distributes more than 41 million free condoms annually.

Philadelphia's design contest began in November and runs through Jan. 14. About a dozen designs have been submitted so far, said Carol Johnson, director of the city Department of Public Health's Division of Disease Control, which is the contest sponsor. Some entries show the city skyline, while others are text-based.

Philadelphia distributes about 1 million free condoms every year to health clinics, schools and other venues. Next year, the city aims to double that number with the help of a $10,000 CDC grant.

"We're trying to push the prevention message," Johnson said. "We're looking for something bold to help promote the use of condoms." Submissions should have a "unique and positive message," she added. The artist of the winning design gets $250.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Alcohol Use, Unprotected Sex, and Sexually Transmitted Infections Among Female Sex Workers in China

"Alcohol use has been suggested to interfere with condom use and to increase sexual risk behaviors," explained the study authors, noting limited data on the prevalence of this practice among female sex workers and its association with condom use and STD infection.

In 2004 in Guangxi, China, 454 establishment-based female sex workers completed a baseline survey for data inclusion in an HIV prevention project. Investigators performed both global association and situational analysis using two measures of alcohol use (alcohol intoxication and consuming alcohol prior to sex with a client). Multiple logistic regression analyses were performed to study the association of alcohol use with women's condom use and STDs.

During the previous six months, one-third of the women reported being intoxicated with alcohol at least once a month, and about 30 percent reported alcohol use prior to having sex with clients. Compared with women who did not use alcohol before engaging in client sex, women who did so reported significantly less condom use and higher rates of both current STD infection and a history of STDs. However, alcohol intoxication was not associated with condom use and STDs. The findings indicate event-specific rather than global associations of alcohol use with STDs and inconsistent condom use, the investigators noted.

"Alcohol use before commercial sex is associated with unprotected sex and increased risk for [STDs]. Interventions that address both alcohol use and HIV risk behaviors in the context of commercial sex may have a great impact on preventing the spread of HIV in China," concluded the authors.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Younger Gay Men in Worrying HIV Trend

In Victoria, younger men who have sex with men may be at an increasing risk of HIV infection, a new study suggests. The finding is based on age-trend comparisons of HIV diagnoses among MSM, using 2000-09 passive and sentinel HIV surveillance data in Victoria and enhanced syphilis and gonorrhea surveillance.

After sustained increases between 2000 and 2007, the median age at HIV diagnosis among MSM in Victoria declined significantly, from 38.8 years in 2007 to 35.3 years in 2008 (P=0.023). Last year, the median age was 35.9 years. Median age at syphilis reports declined, from 40.6 years in 2007 to 36 years, as did the median age at gonorrhea reports in the same period, from 32.3 years to 29.3 years.

Compared with older MSM, MSM below age 35 were less likely to have ever been screened for HIV; more likely to report not knowing the HIV status of regular partners; and more likely to report inconsistent condom use with casual and regular partners.

"Recent focus group data have shown that younger MSM are less likely to discuss HIV and other [STDs] with peers," said study co-author Carol El-Hayek, epidemiologist with the Center for Population Health at Melbourne's Burnet Institute.

"It has also been suggested that younger gay men may be more susceptible to engaging in risky sexual behavior because they are less aware or less concerned about the implications of HIV" in the era of antiretroviral therapy, El-Hayek said.

Between 2000 and 2009, Victoria recorded 1,635 HIV diagnoses among MSM. Between 2007 and 2009, diagnoses among MSM ages 25-29 grew 62 percent.

"Any response developed would need to consider more diverse health strategies to ensure that prevention messages reached young [MSM]," El-Hayek said.

The study, "The Changing Age Distribution of Men Who Have Sex with Men Diagnosed with HIV in Victoria," was published in the Medical Journal of Australia (2010;193(11/12):655-658).

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

US Considers New Tools in Global AIDS Fight

Tuesday, the director of the President's Emergency Plan for AIDS Relief said new methods to slow the spread of HIV may have a place in the program's arsenal. Eric Goosby said PEPFAR is closely monitoring the progress of pre-exposure prophylaxis (PrEP) and microbicide gels.

PrEP involves giving AIDS drugs to uninfected people at high risk for HIV. Last month, new research showed that giving the HIV drugs emtricitabine plus tenofovir to men who have sex with men markedly reduced their risk of contracting HIV.

PEPFAR provides South Africa with approximately $560 million annually. The program recently signed a new five-year deal to help South Africa, which has the world's highest HIV/AIDS caseload. Under the commitment, the United States will help the country identify its HIV/AIDS-fighting priorities and improve its health care infrastructure, said Goosby.

South Africa has proposed using PrEP to treat uninfected inmates, as the country's prisons are major HIV vectors, said Goosby.

"We would support PrEP in terms of high-risk populations," Goosby said, noting that various country approval plans are already under internal consideration.

Microbicide gels, which would be used to protect women from HIV during sex, also could play a part pending additional research and regulatory approval, said Goosby. Results from a South African trial of tenofovir in a gel formula showed it lowered female participants' HIV infection rate by 30 percent.

"We haven't worked out the delivery system or the dosing or interval of application," Goosby noted. "We are absolutely positioned to engage in it as soon as we know those."

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!

Wednesday, December 15, 2010

Promising HIV Prevention Offers Some New Hope

"The recent announcement that a pill currently used to treat HIV infection can also help prevent it was an important milestone in the effort to keep people from getting the virus. . The HIV drug's success in a Phase III trial is one of several recent breakthroughs in HIV prevention. None of the approaches, which also include a vaginal gel and an AIDS vaccine, is perfect, but all are promising.

"Together they add momentum to the growing body of evidence that science, if properly focused and funded, can deliver effective methods of preventing HIV. . Thanks largely to AIDS activists who demanded expedited research and approvals, today there are more drugs licensed to treat HIV than there are for all other viruses combined.

"Generous donors and innovative pricing mechanisms have made these antiretroviral drugs available to about 36 percent of those in the developing world who need them to stay alive and healthy. Increasingly, however, both donor and recipient governments are questioning the sustainability of foreign funding for [ARV] treatment. . It has become clear that treatment for HIV, though still crucially important, can't solve the problem. That will only happen through preventing transmission of the virus in the first place. .

"Though the science for these new tools is promising, the funding base is flat, despite large investments of stimulus dollars by the United States government. . Other donor countries that are contributing to HIV treatment globally should also make simultaneous and significant investments in new prevention methods to ensure that their HIV costs won't rise indefinitely.

"Governments of developing countries can also play their part, by first instituting proven HIV prevention efforts while being accountable for results as measured by reductions in new infections. Second, they can demand the development of new HIV prevention tools as passionately as they have demanded universal access to HIV treatment."

The author is CEO of the non-profit International AIDS Vaccine Initiative.

The Friends of AIDS Foundation is dedicated to enhancing the quality of life for HIV positive individuals and empowering people to make healthy choices to prevent the spread of the HIV virus. To learn more about The Friends of AIDS Foundation, please visit: http://www.friendsofaids.org.


TOGETHER WE REMAIN STRONG!